Molecular Formula | C9H17NO3 |
Molar Mass | 187.24 |
Density | 1.10±0.1 g/cm3(Predicted) |
Melting Point | 117 °C |
Boling Point | 303.7±31.0 °C(Predicted) |
pKa | 12.19±0.40(Predicted) |
Storage Condition | 2-8°C |
use | cis-3-BOC aminocyclobutanol is used as a research compound. |
mechanical compounds using | amino alcohol skeleton structure are widely found in natural products and bioactive molecular structures. these compounds are effective intermediates in pharmaceutical chemistry and provide a lot of research materials for pharmaceutical development. At the same time, the two heteroatoms (N,O) of amino alcohols have high flexibility, and one or two heteroatoms can be used to bond with Lewis acid, transition metal or achiral substrate. It has a wide range of applications in asymmetric synthesis, such as asymmetric reduction and addition of carbonyl groups, asymmetric Diels-Alder cycloaddition reaction, asymmetric 1,2-dipole cycloaddition reaction, Heck reaction, etc. |
preparation | cis -3-aminocyclobutanol is the starting material, and the target compound BOC-cis -3-aminocyclobutanol is prepared by the amino protection of di-tert-butyl dicarbonate. The synthesis reaction formula of BOC-cis -3-aminocyclobutanol is as follows: |